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Laboratory of
Ocular Biomechanics

University of Pittsburgh

Copyright Notice: The publishers hold the copyright of these articles. The PDFs are provided here to ensure rapid dissemination of scholarly work. It is understood that you will use them only in a manner consistent with the fair-use provisions of the relevant copyright laws. You may not distribute them or use them for any commercial enterprise.
Note: Publications are often the result of collaborations, and not all the work was done in our lab.

Publications

See publications of Dr. Sigal in PubMed, Google Scholar and Research Gate.

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  • In-Vivo Effects of Intraocular and Intracranial Pressures on the Lamina Cribrosa Microstructure
  • *B Wang, *H Tran, MA Smith, T Kostanyan, SE Schmitt, RA Bilonick, NJ Jan, L Kagemann, EC Tyler-Kabara, H Ishikawa, JS Schuman, IA Sigal and G Wollstein
  • Accepted by PLOS One on November 6th 2017.
  • (* Authors contributed equally to this manuscript)
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  • In-Vivo Effects of Intraocular and Intracranial Pressures on the Lamina Cribrosa Microstructure
  • *B Wang, *H Tran, MA Smith, T Kostanyan, SE Schmitt, RA Bilonick, NJ Jan, L Kagemann, EC Tyler-Kabara, H Ishikawa, JS Schuman, IA Sigal and G Wollstein
  • Accepted by PLOS One on November 6th 2017.
  • (* Authors contributed equally to this manuscript)
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  • Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult
  • AP Voorhees, NJ Jan, ME Austin, JG Flanagan, JM Sivak, RA Bilonick and IA Sigal
  • Investigative Ophthalmology & Visual Science October 2017, Vol.58, 5336-5346. doi:10.1167/iovs.17-22015
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  • Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult
  • AP Voorhees, NJ Jan, ME Austin, JG Flanagan, JM Sivak, RA Bilonick and IA Sigal
  • Investigative Ophthalmology & Visual Science October 2017, Vol.58, 5336-5346. doi:10.1167/iovs.17-22015
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  • Formalin Fixation and Cryosectioning Cause Only Minimal Changes in Shape or Size of Ocular Tissues
  • H Tran, NJ Jan, D Hu, A Voorhees, JS Schuman, MA Smith, G Wollstein and IA Sigal
  • Sci Rep. 2017 Sept 21;7(1):12065. doi:10.1038/s41598-017-12006-1.
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  • Formalin Fixation and Cryosectioning Cause Only Minimal Changes in Shape or Size of Ocular Tissues
  • H Tran, NJ Jan, D Hu, A Voorhees, JS Schuman, MA Smith, G Wollstein and IA Sigal
  • Sci Rep. 2017 Sept 21;7(1):12065. doi:10.1038/s41598-017-12006-1.
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  • Location of the Central Retinal Vessel Trunk in the Laminar and Prelaminar Tissue of Healthy and Glaucomatous Eyes
  • B Wang, KA Lucy, JS Schuman, H Ishikawa, RA Bilonick, IA Sigal, L Kagemann, C Lu, JG Fujimoto and G Wollstein
  • Sci Rep. 2017 Aug 30; 7(1):9930. doi: 10.1038/s41598-017-10042-5.
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  • Location of the Central Retinal Vessel Trunk in the Laminar and Prelaminar Tissue of Healthy and Glaucomatous Eyes
  • B Wang, KA Lucy, JS Schuman, H Ishikawa, RA Bilonick, IA Sigal, L Kagemann, C Lu, JG Fujimoto and G Wollstein
  • Sci Rep. 2017 Aug 30; 7(1):9930. doi: 10.1038/s41598-017-10042-5.
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  • Effects of collagen microstructure and material properties on the deformation of the neural tissues of the lamina cribrosa
  • AP Voorhees, NJ Jan and IA Sigal
  • Acta Biomaterialia (2017), doi: http://dx.doi.org/10.1016/j.actbio.2017.05.042
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  • Effects of collagen microstructure and material properties on the deformation of the neural tissues of the lamina cribrosa
  • AP Voorhees, NJ Jan and IA Sigal
  • Acta Biomaterialia (2017), doi: http://dx.doi.org/10.1016/j.actbio.2017.05.042
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  • Whole-globe biomechanics using high-field MRI
  • AP Voorhees, LC Ho, NJ Jan, H Tran, Y van der Merwe, K Chan and IA Sigal
  • Exp Eye Res. 2017 Jul;160:85-95. doi: 10.1016/j.exer.2017.05.004.
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  • Whole-globe biomechanics using high-field MRI
  • AP Voorhees, LC Ho, NJ Jan, H Tran, Y van der Merwe, K Chan and IA Sigal
  • Exp Eye Res. 2017 Jul;160:85-95. doi: 10.1016/j.exer.2017.05.004.
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  • Microstructural Crimp of the Lamina Cribrosa and Peripapillary Sclera Collagen Fibers
  • NJ Jan, C Gomez, S Moed, AP Voorhees, JS Schuman, RA Bilonick and IA Sigal
  • Invest Ophthalmol Vis Sci. July 2017; 58:3378–3388. DOI: 10.1167 / iovs.17-21811
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  • Microstructural Crimp of the Lamina Cribrosa and Peripapillary Sclera Collagen Fibers
  • NJ Jan, C Gomez, S Moed, AP Voorhees, JS Schuman, RA Bilonick and IA Sigal
  • Invest Ophthalmol Vis Sci. July 2017; 58:3378–3388. DOI: 10.1167 / iovs.17-21811
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  • Thick Prelaminar Tissue Decreases Lamina Cribrosa Visibility
  • KA Lucy, B Wang, JS Schuman, RA Bilonick, Y Ling, L Kagemann, IA Sigal, I Grulkowski, JJ Liu, JG Fujimoto, H Ishikawa and G Wollstein
  • IOVS, 58(3), 1751-1757, March 2017.
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  • Thick Prelaminar Tissue Decreases Lamina Cribrosa Visibility
  • KA Lucy, B Wang, JS Schuman, RA Bilonick, Y Ling, L Kagemann, IA Sigal, I Grulkowski, JJ Liu, JG Fujimoto, H Ishikawa and G Wollstein
  • IOVS, 58(3), 1751-1757, March 2017.
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  • An imaged-based inverse finite element method to determine in-vivo mechanical properties of human trabecular meshwork
  • AD Pant, L Kagemann, JS Schuman, IA Sigal and R Amini
  • Journal for Modeling in Ophthalmology 2017; 3:100-111
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  • An imaged-based inverse finite element method to determine in-vivo mechanical properties of human trabecular meshwork
  • AD Pant, L Kagemann, JS Schuman, IA Sigal and R Amini
  • Journal for Modeling in Ophthalmology 2017; 3:100-111
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  • Biomechanical aspects of axonal damage in glaucoma: A brief review
  • C Stowell, CF Burgoyne, ER Tamm, CR Ethier, JE Dowling, JC Downs, MH Ellisman, S Fisher, B Fortune, M Fruttiger, T Jakobs, G Lewis, CH Mitchell, J Morrison, SC Sharma, IA Sigal, M Sofroniew, L Wang, J Wiggs, S Wu and RH Masland
  • Exp Eye Res. 2017 Apr;157:13-19. doi: 10.1016/j.exer.2017.02.005
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  • Biomechanical aspects of axonal damage in glaucoma: A brief review
  • C Stowell, CF Burgoyne, ER Tamm, CR Ethier, JE Dowling, JC Downs, MH Ellisman, S Fisher, B Fortune, M Fruttiger, T Jakobs, G Lewis, CH Mitchell, J Morrison, SC Sharma, IA Sigal, M Sofroniew, L Wang, J Wiggs, S Wu and RH Masland
  • Exp Eye Res. 2017 Apr;157:13-19. doi: 10.1016/j.exer.2017.02.005
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  • Biological aspects of axonal damage in glaucoma: A brief review
  • ER Tamm, CR Ethier, CF Burgoyne, CR Ethier, ER Tamm, C Stowell, JE Dowling, JC Downs, MH Ellisman, S Fisher, B Fortune, M Fruttiger, T Jakobs, G Lewis, CH Mitchell, J Morrison, SC Sharma, IA Sigal, M Sofroniew, L Wang, J Wiggs, S Wu and RH Masland
  • Exp Eye Res. 2017 Apr;157:5-12. doi: 10.1016/j.exer.2017.02.006
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  • Biological aspects of axonal damage in glaucoma: A brief review
  • ER Tamm, CR Ethier, CF Burgoyne, CR Ethier, ER Tamm, C Stowell, JE Dowling, JC Downs, MH Ellisman, S Fisher, B Fortune, M Fruttiger, T Jakobs, G Lewis, CH Mitchell, J Morrison, SC Sharma, IA Sigal, M Sofroniew, L Wang, J Wiggs, S Wu and RH Masland
  • Exp Eye Res. 2017 Apr;157:5-12. doi: 10.1016/j.exer.2017.02.006
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  • Correlation between cerebral hemodynamic and perfusion pressure changes in non-human primates
  • A Ruesch, MA Smith, G Wollstein, IA Sigal, S Nelson and JM Kainerstorfer
  • Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100591P (17 February 2017); doi: 10.1117/12.2252550
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  • Correlation between cerebral hemodynamic and perfusion pressure changes in non-human primates
  • A Ruesch, MA Smith, G Wollstein, IA Sigal, S Nelson and JM Kainerstorfer
  • Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100591P (17 February 2017); doi: 10.1117/12.2252550
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  • Collagen architecture of the posterior pole; high-resolution, wide-field-of-view visualization and analysis using polarized light microscopy
  • NJ Jan, K Lathrop and IA Sigal
  • IOVS, 58(2), 735744, Feb 2017. PMID 28146238
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  • Collagen architecture of the posterior pole; high-resolution, wide-field-of-view visualization and analysis using polarized light microscopy
  • NJ Jan, K Lathrop and IA Sigal
  • IOVS, 58(2), 735744, Feb 2017. PMID 28146238
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  • Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures
  • H Tran, J Grimm, B Wang, MA Smith, A Gogola, S Nelson, E Tyler-Kabara, J Schuman, G Wollstein and IA Sigal
  • Proc. SPIE 10067, Optical Elastography and Tissue Biomechanics IV, 100670B (21 February 2017); doi: 10.1117/12.2257360.
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  • Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures
  • H Tran, J Grimm, B Wang, MA Smith, A Gogola, S Nelson, E Tyler-Kabara, J Schuman, G Wollstein and IA Sigal
  • Proc. SPIE 10067, Optical Elastography and Tissue Biomechanics IV, 100670B (21 February 2017); doi: 10.1117/12.2257360.
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  • Identifying the Palisades of Vogt in Human Ex-vivo Tissue
  • IA Sigal, J Steele, S Drexler and KL Lathrop
  • The Ocular Surface 14(4), 435-439, Aug 2016. PMID 27520448
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  • Identifying the Palisades of Vogt in Human Ex-vivo Tissue
  • IA Sigal, J Steele, S Drexler and KL Lathrop
  • AThe Ocular Surface 14(4), 435-439, Aug 2016. PMID 27520448
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  • Non-invasive MRI Assessments of Tissue Microstructures and Macromolecules in the Eye upon Biomechanical or Biochemical Modulation
  • LC Ho, IA Sigal, NJ Jan, X Yang, Y Van der Merwe, Y Yu, Y Chau, CK Leung, IP Conner, T Jin, EX Wu, SG Kim, G Wollstein, JS Schuman and KC Chan
  • Scientific Reports, 6:32080. Aug 26 2016; PMID 27561353. PMCID PMC5000015li>
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  • Non-invasive MRI Assessments of Tissue Microstructures and Macromolecules in the Eye upon Biomechanical or Biochemical Modulation
  • LC Ho, IA Sigal, NJ Jan, X Yang, Y Van der Merwe, Y Yu, Y Chau, CK Leung, IP Conner, T Jin, EX Wu, SG Kim, G Wollstein, JS Schuman and KC Chan
  • Scientific Reports, 6:32080. Aug 26 2016; PMID 27561353. PMCID PMC5000015
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  • Experimental glaucoma causes optic nerve head neural rim tissue compression: a potentially important mechanism of axon injury
  • B Fortune, J Reynaud, C Hardin, L Wang, IA Sigal and CF Burgoyne
  • IOVS, 57(10, 4403-4411, August 2016. PMID 27564522
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  • Experimental glaucoma causes optic nerve head neural rim tissue compression: a potentially important mechanism of axon injury
  • B Fortune, J Reynaud, C Hardin, L Wang, IA Sigal and CF Burgoyne
  • IOVS, 57(10, 4403-4411, August 2016. PMID 27564522
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  • What is a typical optic nerve head?
  • AP Voorhees, JL Grimm, RA Bilonick, L Kagemann, H Ishikawa, JS Schuman, G Wollstein, IA Sigal
  • Experimental Eye Research, 149:40-47, June 2016. PMID: 27339747
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  • What is a typical optic nerve head?
  • AP Voorhees, JL Grimm, RA Bilonick, L Kagemann, H Ishikawa, JS Schuman, G Wollstein, IA Sigal
  • Experimental Eye Research, 149:40-47, June 2016. PMID: 27339747
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  • Decreased lamina cribrosa beam thickness and pore diameter relative to distance from the central retinal vessel trunk
  • B Wang, KA Lucy, JS Schuman, IA Sigal, RA Bilonick, L Kagemann, T Kostanyan, C Lu, J Liu, I Grulkowski, JG Fujimoto, H Ishikawa, G Wollstein
  • Invest Ophthalmol Vis Sci. 2016 Jun 1; 57(7):3088-3092. DOI: 10.1167 / iovs.15-19010
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  • Decreased lamina cribrosa beam thickness and pore diameter relative to distance from the central retinal vessel trunk
  • B Wang, KA Lucy, JS Schuman, IA Sigal, RA Bilonick, L Kagemann, T Kostanyan, C Lu, J Liu, I Grulkowski, JG Fujimoto, H Ishikawa, G Wollstein
  • Invest Ophthalmol Vis Sci. 2016 Jun 1; 57(7):3088-3092. DOI: 10.1167 / iovs.15-19010
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  • Regionally Discrete Aqueous Humor Outflow Quantification Using Fluorescein Canalograms
  • RT Loewen, EN Brown, P Roy, JS Schuman, IA Sigal and NA Loewen
  • PLoS ONE 11(3):e0151754, March 2016. PMID 26998833
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  • Regionally Discrete Aqueous Humor Outflow Quantification Using Fluorescein Canalograms
  • RT Loewen, EN Brown, P Roy, JS Schuman, IA Sigal and NA Loewen
  • PLoS ONE 11(3):e0151754, March 2016. PMID 26998833
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  • A Problem of Proportions in OCT-based Morphometry and a Proposed Solution
  • IA Sigal, JS Schuman, H Ishikawa, L Kagemann and G Wollstein
  • Letter to the Editor, IOVS, 57(2):484-485, Feb 2016.
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  • A Problem of Proportions in OCT-based Morphometry and a Proposed Solution
  • IA Sigal, JS Schuman, H Ishikawa, L Kagemann and G Wollstein
  • Letter to the Editor, IOVS, 57(2):484-485, Feb 2016.
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  • MAPS – A Magic Angle Positioning System for Enhanced Imaging in High-Field Small-Bore MRI
  • A Squires, KC Chan, LC Ho, IA Sigal, NJ Jan and ZTH Tse
  • Journal of Medical Robotics Research 1(1), 1640004, April 2016.
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  • MAPS – A Magic Angle Positioning System for Enhanced Imaging in High-Field Small-Bore MRI
  • A Squires, KC Chan, LC Ho, IA Sigal, NJ Jan and ZTH Tse
  • Journal of Medical Robotics Research 1(1), 1640004, April 2016.
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  • Use and Misuse of Laplace’s Law in Ophthalmology
  • CW Chung, MJA Girard, NJ Jan and IA Sigal
  • Invest Ophthalmol Vis Sci. 2016; 57:236–245. DOI:10.1167 / iovs.15-18053
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  • Use and Misuse of Laplace’s Law in Ophthalmology
  • CW Chung, MJA Girard, NJ Jan and IA Sigal
  • Invest Ophthalmol Vis Sci. 2016; 57:236–245. DOI:10.1167 / iovs.15-18053
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  • Polarization Microscopy for Characterizing Fiber Orientation of Ocular Tissues
  • NJ Jan, JL Grimm, H Tran, KL Lathrop, G Wollstein, RA Bilonick, H Ishikawa, L Kagemann, JS Schuman and IA Sigal
  • Biomedical Optics Express, 6(12):4705-4718. Dec 2015.
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  • Polarization Microscopy for Characterizing Fiber Orientation of Ocular Tissues
  • NJ Jan, JL Grimm, H Tran, KL Lathrop, G Wollstein, RA Bilonick, H Ishikawa, L Kagemann, JS Schuman and IA Sigal
  • Biomedical Optics Express, 6(12):4705-4718. Dec 2015.
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  • Translating Ocular Biomechanics into Clinical Practice: Current State and Future Prospects
  • MJA Girard, WJ Dupps, M Baskaran, G Scarcelli, SH Yun, HA Quigley, IA Sigal and NG Strouthidis
  • Current Eye Research, 40(1):1-18, Jan 2015. PMID 24832392. PMCID 4233020.
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  • Translating Ocular Biomechanics into Clinical Practice: Current State and Future Prospects
  • MJA Girard, WJ Dupps, M Baskaran, G Scarcelli, SH Yun, HA Quigley, IA Sigal and NG Strouthidis
  • Current Eye Research, 40(1):1-18, Jan 2015. PMID 24832392. PMCID 4233020.
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  • Recent Advances in OCT Imaging of the Lamina Cribrosa
  • IA Sigal, B Wang, NG Strouthidis, T Akagi and MJA Girard
  • British Journal of Ophthalmology 98 (Suppl 2), ii34-ii39, Special issue: Advances in Optical Coherence Tomography, July 2014. PMID 24934221
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  • Recent Advances in OCT Imaging of the Lamina Cribrosa
  • IA Sigal, B Wang, NG Strouthidis, T Akagi and MJA Girard
  • British Journal of Ophthalmology 98 (Suppl 2), ii34-ii39, Special issue: Advances in Optical Coherence Tomography, July 2014. PMID 24934221
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  • Glaucomatous cupping of the lamina cribrosa: A review of the evidence for active progressive remodeling as a mechanism
  • JC Downs, MD Roberts and IA Sigal
  • Experimental Eye Research, 93(2):133-140, Aug 2011, PMID 20708001.
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  • Glaucomatous cupping of the lamina cribrosa: A review of the evidence for active progressive remodeling as a mechanism
  • JC Downs, MD Roberts and IA Sigal
  • Experimental Eye Research, 93(2):133-140, Aug 2011, PMID 20708001.
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  • Biomechanics of the Optic Nerve Head
  • IA Sigal, CR Ethier
  • Experimental Eye Research, 88(4):799-807, Apr 2009.
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  • Biomechanics of the Optic Nerve Head
  • IA Sigal, CR Ethier
  • Experimental Eye Research, 88(4):799-807, Apr 2009.
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  • Biomechanical Changes of the Optic Disc
  • IA Sigal, MD Roberts, MJA Girard, CF Burgoyne and JC Down
  • Ocular Disease Chapter 20: Mechanisms and Management, eds. LA Levin and DM Albert, Saunders (Elsevier), 704 Pages, March 2010. ISBN 978-0-7020-2983-7
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  • Biomechanical Changes of the Optic Disc
  • IA Sigal, MD Roberts, MJA Girard, CF Burgoyne and JC Down
  • Chapter 20 in Ocular Disease: Mechanisms and Management, eds. LA Levin and DM Albert, Saunders (Elsevier), 704 Pages, March 2010. ISBN 978-0-7020-2983-7
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  • In Vivo Evaluation of White Matter Inegrity and Anterograde Transport in Visual Systems After Excitoxic Retinal Injury with Multimodal MRI and OCT
  • LC Ho, B Wang, IP Conner, Y Van der Merwe, RA Bilonick, SG Kim, EX Wu, IA Sigal, G Wollstein, JS Schuman and KC Chan
  • Investigative Ophthalmology & Visual Science, 56(6):3788-3800, Jun 2015. PMCID 26066747, PMCID: PMC4468417. [PDF]
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  • In Vivo Evaluation of White Matter Inegrity and Anterograde Transport in Visual Systems After Excitoxic Retinal Injury with Multimodal MRI and OCT
  • LC Ho, B Wang, IP Conner, Y Van der Merwe, RA Bilonick, SG Kim, EX Wu, IA Sigal, G Wollstein, JS Schuman and KC Chan
  • Investigative Ophthalmology & Visual Science, 56(6):3788-3800, Jun 2015. PMCID 26066747, PMCID: PMC4468417.
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  • Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images
  • CL Chen, H Ishikawa, G Wollstein, RA Bilonick, IA Sigal, L Kagemann and JS Schuman
  • Investigative Ophthalmology & Visual Science, 56(6):3810-9, Jun 2015. PMID: 26066749, PMCID:PMC4468911.
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  • Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images
  • CL Chen, H Ishikawa, G Wollstein, RA Bilonick, IA Sigal, L Kagemann and JS Schuman
  • Investigative Ophthalmology & Visual Science, 56(6):3810-9, Jun 2015. PMID: 26066749, PMCID:PMC4468911.
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  • Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
  • L Kagemann, B Wang, G Wollstein, H Ishikawa, B Mentley, IA Sigal, RA Bilonick and JS Schuman
  • Journal of Visualized Experiments, 20(100), Jun 2015. PMID: 26132890.
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  • Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
  • L Kagemann, B Wang, G Wollstein, H Ishikawa, B Mentley, IA Sigal, RA Bilonick and JS Schuman
  • Journal of Visualized Experiments, 20(100), Jun 2015. PMID: 26132890.
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  • Parameters for lithium treatment are critical in its enhancement of fracture-healing in rodents
  • J Bernick, Y Wang, IA Sigal, BA Alman, CM Whyne and D Nam
  • J Bone Joint Surg Am, 96(23): 1990-8, Dec 2014. PMID 25471914
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  • Parameters for lithium treatment are critical in its enhancement of fracture-healing in rodents
  • J Bernick, Y Wang, IA Sigal, BA Alman, CM Whyne and D Nam
  • J Bone Joint Surg Am, 96(23): 1990-8, Dec 2014. PMID 25471914
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  • Application of Elliptic Fourier Analysis to Describe the Lamina Cribrosa Shape with Age and Intraocular Pressure
  • PG Sanfilippo, JL Grimm, JG Flanagan, KL Lathrop and IA Sigal
  • Experimental Eye Research, 128:1-7, Nov 2014. PMID 25193035.
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  • Application of Elliptic Fourier Analysis to Describe the Lamina Cribrosa Shape with Age and Intraocular Pressure
  • PG Sanfilippo, JL Grimm, JG Flanagan, KL Lathrop and IA Sigal
  • Experimental Eye Research, 128:1-7, Nov 2014. PMID 25193035.
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  • In Vivo Three-Dimensional Characterization of the Healthy Human Lamina Cribrosa with Adaptive Optics Spectral-Domain Optical Coherence Tomography
  • Z Nadler, B Wang, JS Schuman, RD Ferguson, A Patel, DX Hammer, RA Bilonick, H Ishikawa, L Kagemann, IA Sigal and G Wollstein
  • Invest Ophthalmol Vis Sci, 55(10):6459-66, Sep 2014. PMCID 4197769
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  • In Vivo Three-Dimensional Characterization of the Healthy Human Lamina Cribrosa with Adaptive Optics Spectral-Domain Optical Coherence Tomography
  • Z Nadler, B Wang, JS Schuman, RD Ferguson, A Patel, DX Hammer, RA Bilonick, H Ishikawa, L Kagemann, IA Sigal and G Wollstein
  • Invest Ophthalmol Vis Sci, 55(10):6459-66, Sep 2014. PMCID 4197769
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  • Magic Angle-Enhanced MRI Of Fibrous Microstructures In Sclera And Cornea With And Without Intraocular Pressure Loading
  • *LC Ho, *IA Sigal, NJ Jan, A Squires, Z Tse, EX Wu, SG Kim, JS Schuman and KC Chan
  • Invest Ophthalmol Vis Sci, 55(9):5662-72, Aug 2014. PMCID 4160095.
  • (* Authors contributed equally to this manuscript)
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  • Magic Angle-Enhanced MRI Of Fibrous Microstructures In Sclera And Cornea With And Without Intraocular Pressure Loading
  • *LC Ho, *IA Sigal, NJ Jan, A Squires, Z Tse, EX Wu, SG Kim, JS Schuman and KC Chan
  • (* Authors contributed equally to this manuscript)
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  • Characterization of Schlemm’s Canal Cross-Sectional Area
  • L Kagemann, JE Nevins, NJ Jan, G Wollstein, H Ishikawa, J Kagemann, IA Sigal, Z Nadler, Y Ling and JS Schuman
  • British Journal of Ophthalmology 98 (Suppl 2), ii10-ii19,Special issue: Advances in Optical Coherence Tomography, July 2014. PMID 24590558.
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  • Characterization of Schlemm’s Canal Cross-Sectional Area
  • L Kagemann, JE Nevins, NJ Jan, G Wollstein, H Ishikawa, J Kagemann, IA Sigal, Z Nadler, Y Ling and JS Schuman
  • British Journal of Ophthalmology 98 (Suppl 2), ii10-ii19,Special issue: Advances in Optical Coherence Tomography, July 2014. PMID 24590558.
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  • A Method to Estimate Biomechanics and Mechanical Properties of Optic Nerve Head Tissues From Parameters Measurable Using Optical Coherence Tomography
  • IA Sigal, JL Grimm, JS Schuman, L Kagemann, H Ishikawa and G Wollstein
  • IEEE Transactions on Medical Imaging, 33(6):1381-9, June 2014. [PDF]
  • Note: the applet associated with this paper is in the Software Page
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  • A Method to Estimate Biomechanics and Mechanical Properties of Optic Nerve Head Tissues From Parameters Measurable Using Optical Coherence Tomography
  • IA Sigal, JL Grimm, JS Schuman, L Kagemann, H Ishikawa and G Wollstein
  • IEEE Transactions on Medical Imaging, 33(6):1381-9, June 2014.
  • Note: the applet associated with this paper is in the Software Page
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  • Reproducibility of In-Vivo OCT Measured Three-Dimensional Human Lamina Cribrosa Microarchitecture
  • B Wang, JE Nevins, Z Nadler, G Wollstein, H Ishikawa, RA Bilonick, L Kagemann, IA Sigal, I Grulkowski, JJ Liu, M Kraus, CD Lu, J Hornegger, JG Fujimoto and JS Schuman
  • PLOS ONE 9(4):e95526, April 2014. PMID 24747957
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  • Reproducibility of In-Vivo OCT Measured Three-Dimensional Human Lamina Cribrosa Microarchitecture
  • B Wang, JE Nevins, Z Nadler, G Wollstein, H Ishikawa, RA Bilonick, L Kagemann, IA Sigal, I Grulkowski, JJ Liu, M Kraus, CD Lu, J Hornegger, JG Fujimoto and JS Schuman
  • PLoS ONE 9(4):e95526, April 2014. PMID 24747957
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  • IOP Elevation Reduces Schlemm’s Canal Cross-sectional Area
  • L Kagemann, B Wang, G Wollstein, H Ishikawa, JE Nevins, Z Nadler, IA Sigal, RA Bilonick and JS Schuman
  • Invest Ophthalmol Vis Sci, 55(3):1805-1809, March 2014.
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  • IOP Elevation Reduces Schlemm’s Canal Cross-sectional Area
  • L Kagemann, B Wang, G Wollstein, H Ishikawa, JE Nevins, Z Nadler, IA Sigal, RA Bilonick and JS Schuman
  • Invest Ophthalmol Vis Sci, 55(3):1805-1809, March 2014.
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  • Repeatability of in vivo 3D lamina cribrosa microarchitecture using adaptive optics spectral domain optical coherence tomography
  • Z Nadler, B Wang, G Wollstein, JE Nevins, H Ishikawa, R Bilonick, L Kagemann, IA Sigal, RD Ferguson, A Patel, DX Hammer and JS Schuman
  • Biomedical Optics Express, 5(4):1114-1123 April 1,2014
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  • Repeatability of in vivo 3D lamina cribrosa microarchitecture using adaptive optics spectral domain optical coherence tomography
  • Z Nadler, B Wang, G Wollstein, JE Nevins, H Ishikawa, R Bilonick, L Kagemann, IA Sigal, RD Ferguson, A Patel, DX Hammer and JS Schuman
  • Biomedical Optics Express, 5(4):1114-1123 April 1,2014
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  • Gold Nanorods as a Contrast Agent for Doppler Optical Coherence Tomography
  • B Wang, L Kagemann, JS Schuman, H Ishikawa, RA Bilonick, Y Ling, IA Sigal, Z Nadler, A Francis, MG Sandrian and G Wollstein
  • PLOS One, 9(3): e90690 March 3, 2014
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  • Gold Nanorods as a Contrast Agent for Doppler Optical Coherence Tomography
  • B Wang, L Kagemann, JS Schuman, H Ishikawa, RA Bilonick, Y Ling, IA Sigal, Z Nadler, A Francis, MG Sandrian and G Wollstein
  • PLOS One, 9(3): e90690 March 3, 2014
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  • In-Vivo Lamina Cribrosa Microarchitecture in Healthy and Glaucomatous Eyes as Assessed by Optical Coherence Tomography
  • B Wang, JE Nevins, Z Nadler, G Wollstein, H Ishikawa, RA Bilonick, L Kagemann, IA Sigal, I Grulkowski, JJ Liu, M Kraus, CD Lu, J Hornegger, JG Fujimoto and JS Schuman
  • Invest Ophthalmol Vis Sci, 54(13):8270-8274, Dec 2013. PMID 24302585.
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  • In-Vivo Lamina Cribrosa Microarchitecture in Healthy and Glaucomatous Eyes as Assessed by Optical Coherence Tomography
  • B Wang, JE Nevins, Z Nadler, G Wollstein, H Ishikawa, RA Bilonick, L Kagemann, IA Sigal, I Grulkowski, JJ Liu, M Kraus, CD Lu, J Hornegger, JG Fujimoto and JS Schuman
  • Invest Ophthalmol Vis Sci, 54(13):8270-8274, Dec 2013. PMID 24302585.
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  • Automated Lamina Cribrosa Microstructural Segmentation in Optical Coherence Tomography Scans of Healthy and Glaucomatous Eyes
  • Z Nadler, B Wang, G Wollstein, J Nevins, H Ishikawa, L Kagemann, IA Sigal, RD Ferguson, DX Hammer, I Grulkowski, JJ Liu, MF Kraus, CD Lu, J Hornegger, JG Fujimoto and JS Schuman
  • Biomedical Optics Express, 4(11): 2596-2608, Nov 2013. [PDF]
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  • Automated Lamina Cribrosa Microstructural Segmentation in Optical Coherence Tomography Scans of Healthy and Glaucomatous Eyes
  • Z Nadler, B Wang, G Wollstein, J Nevins, H Ishikawa, L Kagemann, IA Sigal, RD Ferguson, DX Hammer, I Grulkowski, JJ Liu, MF Kraus, CD Lu, J Hornegger, JG Fujimoto and JS Schuman
  • Biomedical Optics Express, 4(11): 2596-2608, Nov 2013.
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  • Signal Normalization Reduces Systematic Measurement Differences Between Spectral Domain Optical Coherence Tomography Devices
  • CL Chen, H Ishikawa, Y Ling, G Wollstein, RA Bilonick, J Xu, JG Fujimoto, IA Sigal, L Kagemann and JS Schuman
  • Invest Ophthalmol Vis Sci, 54(12):7317-7322, Nov 2013. PMID 24114534.
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  • Signal Normalization Reduces Systematic Measurement Differences Between Spectral Domain Optical Coherence Tomography Devices
  • CL Chen, H Ishikawa, Y Ling, G Wollstein, RA Bilonick, J Xu, JG Fujimoto, IA Sigal, L Kagemann and JS Schuman
  • Invest Ophthalmol Vis Sci, 54(12):7317-7322, Nov 2013. PMID 24114534.
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  • Individual A-Scan Signal Normalization Between Two Spectral Domain Optical Coherence Tomography Devices
  • CL Chen, H Ishikawa, G Wollstein, Y Ling, RA Bilonick, L Kagemann, IA Sigal and JS Schuman
  • Invest Ophthalmol Vis Sci, 54(5):3463-3471, May 2013. PMID 23611992.
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  • Individual A-Scan Signal Normalization Between Two Spectral Domain Optical Coherence Tomography Devices
  • CL Chen, H Ishikawa, G Wollstein, Y Ling, RA Bilonick, L Kagemann, IA Sigal and JS Schuman
  • Invest Ophthalmol Vis Sci, 54(5):3463-3471, May 2013. PMID 23611992.
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  • High Dynamic Range Imaging Concept-Based Signal Enhancement Method Reduced the Optical Coherence Tomography Measurement Variability
  • H Ishikawa, CL Chen, G Wollstein, JL Grimm, Y Ling, RA Bilonick, IA Sigal, L Kagemann and JS Schuman
  • Invest Ophthalmol Vis Sci, 54(1):836-41, Jan 2013. PMID 23299477. [PDF]
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  • High Dynamic Range Imaging Concept-Based Signal Enhancement Method Reduced the Optical Coherence Tomography Measurement Variability
  • H Ishikawa, CL Chen, G Wollstein, JL Grimm, Y Ling, RA Bilonick, IA Sigal, L Kagemann and JS Schuman
  • Invest Ophthalmol Vis Sci, 54(1):836-41, Jan 2013. PMID 23299477.
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  • Human Lamina Cribrosa Insertion and Age
  • IA Sigal, JG Flanagan, KL Lathrop, I Tertinegg and R Bilonick
  • Invest Ophthalmol Vis Sci, 53(11):6780-9, Oct 2012. PMID 22956611.
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  • Human Lamina Cribrosa Insertion and Age
  • IA Sigal, JG Flanagan, KL Lathrop, I Tertinegg and R Bilonick
  • Invest Ophthalmol Vis Sci, 53(11):6780-9, Oct 2012. PMID 22956611.
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  • Morphometric Analysis of Aqueous Humor Outflow Structures with Spectral Domain Optical Coherence Tomography
  • AW Francis, L Kagemann, G Wollstein, H Ishikawa, S Folz, D Overby, IA Sigal, B Wang and JS Schuman
  • Invest Opthalmol Vis Sci, 53(9):5198-207, Sep 2012.
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  • Morphometric Analysis of Aqueous Humor Outflow Structures with Spectral Domain Optical Coherence Tomography
  • AW Francis, L Kagemann, G Wollstein, H Ishikawa, S Folz, D Overby, IA Sigal, B Wang and JS Schuman
  • Invest Opthalmol Vis Sci, 53(9):5198-207, Sep 2012.
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  • 3D Visualization of Aqueous Outflow Structures In the Living Human Eye
  • L Kagemann, G Wollstein, H Ishikawa, Z Nadler, IA Sigal, LS Folio and JS Schuman
  • Ophthalmology, 119(8):1563-8, Aug 2012.
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  • 3D Visualization of Aqueous Outflow Structures In the Living Human Eye
  • L Kagemann, G Wollstein, H Ishikawa, Z Nadler, IA Sigal, LS Folio and JS Schuman
  • Ophthalmology, 119(8):1563-8, Aug 2012.
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  • A few good responses. Which mechanical effects of IOP on the ONH to study?
  • IA Sigal, JL Grimm
  • Invest Ophthalmol Vis Sci, 53(7):4270-8. June 2012.
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  • A few good responses. Which mechanical effects of IOP on the ONH to study?
  • IA Sigal, JL Grimm
  • Invest Ophthalmol Vis Sci, 53(7):4270-8. June 2012.
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  • The Optic Nerve Head As A Robust Biomechanical System
  • IA Sigal,RA Bilonick, L Kagemann, G Wollstein, H Ishikawa, JS Schuman and JL Grimm
  • Invest Ophthalmol Vis Sci, 53(6):2658-67, May 2012.
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  • The Optic Nerve Head As A Robust Biomechanical System
  • IA Sigal,RA Bilonick, L Kagemann, G Wollstein, H Ishikawa, JS Schuman and JL Grimm
  • Invest Ophthalmol Vis Sci, 53(6):2658-67, May 2012.
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  • Lamina Cribrosa Thickening in Early Glaucoma Predicted by a Microstructure Driven Growth and Remodeling Approach
  • R Grytz, IA Sigal, JW Ruberti, G Meschke and JC Downs
  • Mechanics of Materials, 44:99-109. 2012.
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  • Lamina Cribrosa Thickening in Early Glaucoma Predicted by a Microstructure Driven Growth and Remodeling Approach
  • R Grytz, IA Sigal, JW Ruberti, G Meschke and JC Downs
  • Mechanics of Materials, 44:99-109. 2012.
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  • Effect of Acute Intraocular Pressure Elevation on the Monkey Optic Nerve Head as Detected by Spectral Domain Ocular Coherence Tomography
  • NG Strouthidis, B Fortune, H Yang, IA Sigal and CF Burgoyne
  • Invest Ophthalmol Vis Sci, 52(12):9431-37, Dec 2011.
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  • Effect of Acute Intraocular Pressure Elevation on the Monkey Optic Nerve Head as Detected by Spectral Domain Ocular Coherence Tomography
  • NG Strouthidis, B Fortune, H Yang, IA Sigal and CF Burgoyne
  • Invest Ophthalmol Vis Sci, 52(12):9431-37, Dec 2011.
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  • IOP-induced lamina cribrosa displacement and scleral canal expansion. Are they independent or related?
  • IA Sigal, H Yang, MD Roberts, JL Grimm, CF Burgoyne, S Demirel and JC Downs
  • Invest Ophthalmol Vis Sci, 52(12):9023-32. Dec 2011. PMID 21989723.
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  • IOP-induced lamina cribrosa displacement and scleral canal expansion. Are they independent or related?
  • IA Sigal, H Yang, MD Roberts, JL Grimm, CF Burgoyne, S Demirel and JC Downs
  • Invest Ophthalmol Vis Sci, 52(12):9023-32. Dec 2011. PMID 21989723.
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  • 3D Visualization of Aqueous Outflow Structures In-Situ in Humans
  • L Kagemann, G Wollstein, H Ishikawa, IA Sigal, LS Folio, J Xu, H Gong and JS Schuman
  • Experimental Eye Research 93(3):308-315 Camras Special Issue Sep 2011.
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  • 3D Visualization of Aqueous Outflow Structures In-Situ in Humans
  • L Kagemann, G Wollstein, H Ishikawa, IA Sigal, LS Folio, J Xu, H Gong and JS Schuman
  • Experimental Eye Research 93(3):308-315 Camras Special Issue Sep 2011.
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  • Posterior (outward) migration of the lamina cribrosa and early cupping in monkey experimental glaucoma
  • H Yang, G Williams, JC Downs, IA Sigal, MD Roberts, H Thompson and CF Burgoyne
  • Invest Ophthalmol Vis Sci, 52(10):7109-7921, Sep 2011. PMID 21715355
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  • Posterior (outward) migration of the lamina cribrosa and early cupping in monkey experimental glaucoma
  • H Yang, G Williams, JC Downs, IA Sigal, MD Roberts, H Thompson and CF Burgoyne
  • Invest Ophthalmol Vis Sci, 52(10):7109-7921, Sep 2011. PMID 21715355
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  • An Applet to Estimate the IOP-Induced Stress and Strain Within the Optic Nerve Head
  • IA Sigal
  • Invest Ophthalmol Vis Sci, 52(8):5497-506, Jul 2011. PMID 21527378.
  • Note: The applet associated with this paper is in the Software page.
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  • An Applet to Estimate the IOP-Induced Stress and Strain Within the Optic Nerve Head
  • IA Sigal
  • Invest Ophthalmol Vis Sci, 52(8):5497-506, Jul 2011. PMID 21527378.
  • Note: The applet associated with this paper is in the Software page.
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  • Finite Element Modeling of the Human Sclera: Influence on Optic Nerve Head Biomechanics and Connections with Glaucoma
  • R Norman, JG Flanagan, IA Sigal, S Rausch, I Tertinegg and CR Ethier
  • Experimental Eye Research, Jul 2011. PMID 20883693.
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  • Finite Element Modeling of the Human Sclera: Influence on Optic Nerve Head Biomechanics and Connections with Glaucoma
  • R Norman, JG Flanagan, IA Sigal, S Rausch, I Tertinegg and CR Ethier
  • Experimental Eye Research, Jul 2011. PMID 20883693.
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  • IOP-Induced Lamina Cribrosa Displacement and Scleral Canal Expansion: an Analysis of Factor Interactions Using Parameterized Eye-Specific Models
  • IA Sigal, H Yang, MD Roberts, CF Burgoyne and JC Downs
  • Invest Ophthalmol Vis Sci, 52(3):1896-1907. Mar 2011. PMID 20881292.
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  • IOP-Induced Lamina Cribrosa Displacement and Scleral Canal Expansion: an Analysis of Factor Interactions Using Parameterized Eye-Specific Models
  • IA Sigal, H Yang, MD Roberts, CF Burgoyne and JC Downs
  • Invest Ophthalmol Vis Sci, 52(3):1896-1907. Mar 2011. PMID 20881292.
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  • Longitudinal Change Detected by Spectral Domain Optical Coherence Tomography in the Glaucomatous Optic Nerve Head and Peripapillary Retina
  • NG Strouthidis, B Fortune, H Yang, IA Sigal and CF Burgoyne
  • Invest Ophthalmol Vis Sci, 52(3):1206-19, Mar 2011.
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  • Longitudinal Change Detected by Spectral Domain Optical Coherence Tomography in the Glaucomatous Optic Nerve Head and Peripapillary Retina
  • NG Strouthidis, B Fortune, H Yang, IA Sigal and CF Burgoyne
  • Invest Ophthalmol Vis Sci, 52(3):1206-19, Mar 2011.
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  • Deformation of the Early Glaucomatous Monkey Optic Nerve Head Connective Tissue Following Acute IOP Elevation Within 3-D Histomorphometric Reconstructions
  • H Yang, H Thompson, MD Roberts, IA Sigal, JC Downs and CF Burgoyne
  • Invest Ophthalmol Vis Sci, 52(1):345-63, Jan 2011.
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  • Deformation of the Early Glaucomatous Monkey Optic Nerve Head Connective Tissue Following Acute IOP Elevation Within 3-D Histomorphometric Reconstructions
  • H Yang, H Thompson, MD Roberts, IA Sigal, JC Downs and CF Burgoyne
  • Invest Ophthalmol Vis Sci, 52(1):345-63, Jan 2011.
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  • Changes in the Biomechanical Response of the Optic Nerve Head in Early Experimental Glaucoma
  • MD Roberts, IA Sigal, Yi Liang, CF Burgoyne and JC Downs
  • Invest Ophthalmol Vis Sci, 51(11):5675-5684. Nov 2010, PMID 20538997
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  • Changes in the Biomechanical Response of the Optic Nerve Head in Early Experimental Glaucoma
  • MD Roberts, IA Sigal, Yi Liang, CF Burgoyne and JC Downs
  • Invest Ophthalmol Vis Sci, 51(11):5675-5684. Nov 2010, PMID 20538997
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  • A Geometric Morphometric Assessment of the Optic Cup in Glaucoma
  • PG Sanfilippo, A Cardini, IA Sigal, J Ruddle, BE Chua, AW Hewitt, and DA Mackey
  • Experimental Eye Research, 91(3): 405-414, Sep 2010.
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  • A Geometric Morphometric Assessment of the Optic Cup in Glaucoma
  • PG Sanfilippo, A Cardini, IA Sigal, J Ruddle, BE Chua, AW Hewitt, and DA Mackey
  • Experimental Eye Research, 91(3): 405-414, Sep 2010.
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  • Dimensions of the Human Sclera: Thickness Measurement and Regional Changes with Axial Length
  • R Norman, JG Flanagan, S Rausch, IA Sigal, I Tertinegg, A Eilaghi, S Portnoy, J Sled and CR Ethier
  • Experimental Eye Research, 90(2): 277-284, Feb 2010.
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  • Dimensions of the Human Sclera: Thickness Measurement and Regional Changes with Axial Length
  • R Norman, JG Flanagan, S Rausch, IA Sigal, I Tertinegg, A Eilaghi, S Portnoy, J Sled and CR Ethier
  • Experimental Eye Research, 90(2): 277-284, Feb 2010.
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  • 3D morphometry of the Human Optic Nerve Head
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Experimental Eye Research, 90(1):70-80, Jan 2010.
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  • 3D morphometry of the Human Optic Nerve Head
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Experimental Eye Research, 90(1):70-80, Jan 2010.
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  • Mesh Morphing and Response Surface Analysis: Quantifying Sensitivity of Vertebral Mechanical Behaviour
  • IA Sigal and CM Whyne
  • Annals of Biomedical Engineering, 38(1):41-56, Jan 2010.
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  • Mesh Morphing and Response Surface Analysis: Quantifying Sensitivity of Vertebral Mechanical Behaviour
  • IA Sigal and CM Whyne
  • Annals of Biomedical Engineering, 38(1):41-56, Jan 2010.
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  • Morphing Methods to Parameterize Specimen-Specific Finite Element Model Geometries
  • IA Sigal, H Yang, MD Roberts and JC Downs
  • Journal of Biomechanics, 43(2):254-262. 19, Jan 2010.
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  • Morphing Methods to Parameterize Specimen-Specific Finite Element Model Geometries
  • IA Sigal, H Yang, MD Roberts and JC Downs
  • Journal of Biomechanics, 43(2):254-262. 19, Jan 2010.
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  • Correlation Between Local Stress and Strain and Lamina Cribrosa Connective Tissue Volume Fraction in Normal Monkey Eyes
  • MD Roberts, Y Liang, IA Sigal, J Grimm, J Reynaud, A Bellezza, CF Burgoyne and JC Downs
  • Invest Ophthalmol Vis Sci, 51(1):295-307, Jan 2010.
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  • Correlation Between Local Stress and Strain and Lamina Cribrosa Connective Tissue Volume Fraction in Normal Monkey Eyes
  • MD Roberts, Y Liang, IA Sigal, J Grimm, J Reynaud, A Bellezza, CF Burgoyne and JC Downs
  • Invest Ophthalmol Vis Sci, 51(1):295-307, Jan 2010.
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  • Deformation of the Normal Monkey Optic Nerve Head Connective Tissues Following Acute IOP Elevation Within 3-D Histomorphometric Reconstructions
  • H Yang, JC Downs, IA Sigal, M Roberts, H Thompson, CF Burgoyne
  • Invest Ophthalmol Vis Sci, 50(12): 5785-5789. Dec 2009.
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  • Deformation of the Normal Monkey Optic Nerve Head Connective Tissues Following Acute IOP Elevation Within 3-D Histomorphometric Reconstructions
  • H Yang, JC Downs, IA Sigal, M Roberts, H Thompson, CF Burgoyne
  • Invest Ophthalmol Vis Sci, 50(12): 5785-5789. Dec 2009.
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  • Interactions Between Geometry and Mechanical Properties on the Optic Nerve Head
  • IA Sigal
  • Invest Ophthalmol Vis Sci, 50(6): 2785-95. Jun 2009.
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  • Interactions Between Geometry and Mechanical Properties on the Optic Nerve Head
  • IA Sigal
  • Invest Ophthalmol Vis Sci, 50(6): 2785-95. Jun 2009.
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  • Modeling Individual-Specific Human Optic Nerve Head Biomechanics Part II: Influence of Material Properties
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Biomech Model Mechanobiol, 8(2):99-109, Apr 2009.
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  • Modeling Individual-Specific Human Optic Nerve Head Biomechanics Part II: Influence of Material Properties
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Biomech Model Mechanobiol, 8(2):99-109, Apr 2009.
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  • Modeling Individual-Specific Human Optic Nerve Head Biomechanics Part I: IOP-Induced Deformations and Influence of Geometry
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Biomech Model Mechanobiol, 8(2):85-98, Apr 2009.
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  • Modeling Individual-Specific Human Optic Nerve Head Biomechanics Part I: IOP-Induced Deformations and Influence of Geometry
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Biomech Model Mechanobiol, 8(2):85-98, Apr 2009.
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  • Mesh-Morphing Algorithms for Specimen-Specific Finite Element Modeling
  • IA Sigal, MR Hardisty and CM Whyne
  • J Biomech, 41(7):1381-1389, 2008.
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  • Mesh-Morphing Algorithms for Specimen-Specific Finite Element Modeling
  • IA Sigal, MR Hardisty and CM Whyne
  • J Biomech, 41(7):1381-1389, 2008.
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  • Predicted Extension, Compression and Shearing of Optic Nerve Head Tissues
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Experimental Eye Research, 85(3):312-322, Sep 2007.
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  • Predicted Extension, Compression and Shearing of Optic Nerve Head Tissues
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Experimental Eye Research, 85(3):312-322, Sep 2007.
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  • Factors Influencing Human Optic Nerve Head Biomechanics
  • IA Sigal, JG Flanagan and CR Ethier
  • Invest Ophthalmol Vis Sci, 46(11): 4189-4199, Nov 2005.
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  • Factors Influencing Human Optic Nerve Head Biomechanics
  • IA Sigal, JG Flanagan and CR Ethier
  • Invest Ophthalmol Vis Sci, 46(11): 4189-4199, Nov 2005.
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  • Reconstruction of Human Optic Nerve Heads for Finite Element Modeling
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Technology and Health Care: Official Journal of the European Society for Engineering and Medicine, 13(4): 313-329, Aug 2005.
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  • Reconstruction of Human Optic Nerve Heads for Finite Element Modeling
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Technology and Health Care: Official Journal of the European Society for Engineering and Medicine, 13(4): 313-329, Aug 2005.
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  • Finite Element Modeling of Optic Nerve Head Biomechanics
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Invest Ophthalmol Vis Sci, 45(12): 4378-4387, Dec 2004.
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  • Finite Element Modeling of Optic Nerve Head Biomechanics
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Invest Ophthalmol Vis Sci, 45(12): 4378-4387, Dec 2004.
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  • Investigation Of The Biomechanical Environment Within The Optic Nerve Head By Finite Element Modelling
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Computational Fluid and Solid Mechanics, 2nd MIT Conference on, Boston, Jun1 17-20, 2003, K.J. Bathe (ed.), pp. 1810-1813, Elsevier (ISBN: 0-08-044046-0), 2003.
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  • Investigation Of The Biomechanical Environment Within The Optic Nerve Head By Finite Element Modelling
  • IA Sigal, JG Flanagan, I Tertinegg and CR Ethier
  • Computational Fluid and Solid Mechanics, 2nd MIT Conference on, Boston, Jun1 17-20, 2003, K.J. Bathe (ed.), pp. 1810-1813, Elsevier (ISBN: 0-08-044046-0), 2003.
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  • Chirality in Bare and Passivated Gold Nanoclusters
  • IL Garzón, JA Reyes-Nava, JI Rodríguez-Hernández, I Sigal, MR Beltrán and K Michaelian
  • Phys. Rev. B 66(7), 073403, Aug 2002.
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  • Chirality in Bare and Passivated Gold Nanoclusters
  • IL Garzón, JA Reyes-Nava, JI Rodríguez-Hernández, I Sigal, MR Beltrán and K Michaelian
  • Phys. Rev. B 66(7), 073403, Aug 2002.